Black Pearl Technology (BPT) is a modified blood-taking syringe filled with glass beads coated with a unique biopolymer (nano-carbonaceous materials). The polymer can stimulate blood cells to produce and release highest possible amount of necessary proteins for tissue repair into the serum. A novel method for preparing an autologous serum enriched in growth factors and cytokines. BPT delivers an intelligent, natural painkiller and powerful healer serum from the patient's blood without adding chemicals or drugs. In laboratory studies, human or animal mono-nuclear blood cells like monocytes and platelets synthesize and release high concentrations of growth factors and regenerative cytokines.